The Doctrinal Committee of the United States Conference of Catholic Bishops (USCCB) issued on 20 Marcha 14-page firm doctrinal note on the "Moral Limits to Technological Manipulation of the Human Body".

It sets out clearly the prohibition on “manipulating” or mutilating the bodies of people, especially young people, with the aim of changing sex, stating: “Catholic health care services must not perform interventions, whether surgical or chemical, that aim to transform the sexual characteristics of a human body into those of the opposite sex or take part in the development of such procedures.”