Twenty-two Catholic missionaries were killed around the world in 2021, half of them in Africa, according to a report released by the Fides News Agency.

Fides, the news agency of the Congregation for the Evangelization of Peoples, reported that of the 22 missionaries killed in 2021, 13 were priests, two were women religious, one was a male religious, and six were lay people. Half of the total were killed in Africa: seven priests, two religious sisters, and two lay people.

In its report, Fides explains that their annual list "has not only included missionaries ad gentes in the strict sense, but has tried to register all Catholic Christians engaged in some way in a pastoral activity who died violently, not expressly 'in hatred of the faith'."