This year’s US Leaders Special Report reflects the new realities of American public affairs. As one Catholic left the White House after Joe Biden decided, at last, to withdraw from seeking a second term of office, Donald Trump returned to power with another—JD Vance—as his vice president, and a cabinet packed with conservatives who wear their faith on their sleeve.

In this first section of the report, we look at those who have made a significant impact in business and philanthropy. From startup garages to boardrooms and family foundations, these Catholic leaders show how enterprise and generosity can reinforce each other. They have built companies, backed founders, and reinvested their returns into schools, scholarships, clinics, research, parish life and culture—often taking risks on places and projects others overlook.